Alfie Evans died at Alder Hey children’s hospital in Liverpool in the early hours of Saturday morning.
Announcing the news on Facebook on Saturday, his parents, Kate James and Thomas Evans, said: “Our baby boy grew his wings tonight at 2:30am. We are heart broken. Thank you everyone for all your support.”
Life support was withdrawn on Monday after a last-ditch appeal to the high court was turned down.
Alfie had been in a semi-vegetative state and scans of his brain had shown that almost all of it had been destroyed. Judges had agreed with doctors that further treatment would be futile and there was no hope of him getting better.
His parents, who are both in their early 20s and from Liverpool, had insisted their son was not in pain or suffering, but lost cases in the high court, court of apeal supreme court and European court of human rights
Evans said on Thursday that their lives had been turned upside down by the intense focus his son’s case had received in Britain and around the world.
“Our little family along with Alder Hey has become the centre of attention for many people around the world and it has meant we have not been able to live our lives as we would like,” he said.